You might need to provide more detail, but if you are wondering if you can do this, the answer is yes. The syntax would look like this:
CASE WHEN fieldname NOT IN ('Georgia','Alabama','Texas') THEN 'exclude' ELSE 'include' END
Thank you but it literally started working after I posted it so I tried to delete my post and could only delete the context and not the post. No clue but it's working.
Thank you @MarkSnodgrass