I change this default literally every time I add a field to a table and elsewhere in Domo. It's extra clicks each time (per field added to a table). Additionally, when other users create their own reports they rarely change the default behavior and it remains at two decimals, which reduces data comprehension.
For example, when the number is 1,520,400.94 I rarely care about that 94 cents and it's harder to perceive the number accurately.
Hope this is a frustration for others so that you enable a default to be set!